Abstract – Successful bioherbicide commercialization for Striga witchweed and next steps in Africa and globally

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Abstract

The Toothpick Project’s innovation, developed over four decades and commercialized in 2021, uses strains of Fusarium oxysporum f.sp. strigae selected for overproduction and excretion of specific amino acids, killing the parasitic weed Striga hermonthica (witchweed), Africa’s worst pest threat to food security. The seed coating product, Kichawi KillTM, safely and affordably helps farmers restore their crop yield with an average increase of 37-65%. Historically, bioherbicides have not been a sufficient alternative to the dominant use of synthetic chemical herbicides. To be used safely as bioherbicides, plant pathogens need to be host specific, non-toxic, and yet sufficiently virulent to control a specific weed. For commercialization, bioherbicides must be affordable and require a sufficient shelf life for distribution. Given the current triple storm encountered by the chemical herbicide industry (herbicide-resistant weeds, lawsuits, and consumer pushback), there exists an opportunity to use certain plant pathogens as bioherbicides by enhancing their virulence. By discussing barriers in the scope of knowledge, policy, and finance in the development of the Toothpick Project’s new microbial bioherbicide, we hope to help others to anticipate the challenges and provide change-leaders a ground level perspective of bioherbicide development.

keywords 

Biocontrol

striga

bioherbicide

fusarium

mycoherbicide 

Highlights 

 Kichawi Kill is a strain of Fusarium oxysporum f.sp. strigae selected for amino acid overproduction 

Striga (witchweed), an invasive parasitic weed on staple crops in Africa, finally has a solution 

The virulence-enhancement platform technology can be developed for other weeds globally